Course Offerings

Fall Courses

Course #
Course Title
Crdts
Instructor
BCBH-502
Biotechnology Industry Internship
4
Chirikjian and Nontanovan
BCHB-507
Laboratory Applications of Biotechnology
3
Helling, Nontanovan and Chirikjian
BCHB-509
Introduction to the Biotechnology Industry
3
Chirikjian and Guests
BCHB-513
Core Concepts of Biochemistry & Molecular Biology
4
Rosenthal C. and Faculty
BCHB-514
Introduction to Bioinformatics
1
Chirikjian and Staff
BCHB-516
Molecular Medicine
2
Ascione
BCHB-521
Bioinformatics
3
Danielsen and Mazumder
BCHB-523
Intellectual Property
1
House, Millstein and Chirikjian
BCHB-526
Core Methods of Biotechnology
3
Rosenthal D. and Faculty
BCHB-535
Programmed Cell Death
2
Rosenthal C.
BCHB-562
Biotech and World Food Production
2
Lesney
BCHB-902
Biotechnology Tutorial
1-4
Staff
BCHB-903
Biochemistry Tutorial
1-4
Rosenthal C.
BCHB-910
Biochemistry/Molecular Biology Internship
4
Rosenthal C.

Green - Biotechnology Core Courses
Orange - Biochemistry/Molecular Biology Core Courses
Purple - Both Programs

Spring Courses

Course #
Course Title
Crdts
Instructor
BCHB-502
Biotechnology Industry Internship
4
Nontanovan and Chirikjian
BCHB-508
Laboratory Applications of Biotechnology
3
Helling, Nontanovan and Chirikjian
BCHB-510
Entrepreneurial Biotechnology
3
Chirikjian
BCHB-515
Introduction to Bioinformatics
1
Vasudevan
BCHB-516
Molecular Medicine
2
Ascione
BCHB-520
Financial Matrix for Biotechnology
1
Chirikjian and Faculty
BCHB-522
Special Topics: Drug Target & Design
1
Eiden and Chirikjian
BCHB-525
Immunobiotechnology
2
Kisailus
BCHB-526
Core Methods of Biotechnology
3
TBD
BCHB-527
Food Biotechnology
2
Labuda
BCHB-529
Biotechnology-Based Human Diagnostics
2
Hartmann and Nontanovan
BCHB-533
Emerging Biotechnology Concepts
2
Millstein and House
BCHB-536
Applications of Cell Culture in Biotechnology & Medicine
2
Rosenthal C.
BCHB-537
Fermentation in Bioprocessing
1
Shiloach and Nontanovan
BCHB-539
Basic Radiation Safety
0
Martin
BCHB-540
Molecular Basis of Carcinogenesis
3
Kasid and Guests
BCHB-541
Structural Biology
3
Vasudevan
BCHB-543
Current Good Manufacturing Practices
1
Mintz
BCHB-902
Biotechnology Tutorial
1-4
Staff
BCHB-903
Biochemistry Tutorial
1-4
Rosenthal C.
BCHB-910
Biochemistry/Molecular Biology Internship
4
Rosenthal C.
PHAR-534
Ethical Issues in Scientific Research*
2
Schwartz

Green - Biotechnology Core Courses
Orange - Biochemistry/Molecular Biology Core Courses
Purple - Both Programs
*Course not offered in the department

Course Offerings for M.S. Degree Programs

COURSE # TITLE (CREDITS) (Click on course title for syllabus)

Core Courses

BCHB-502 Biotechnology Industry Internship(4 Fall/Spring)

BCHB-507, 508 Laboratory Applications of Biotechnology(3 Fall/Spring)

BCHB-509 Introduction to the Biotechnology Industry(3 Fall)

BCHB-510 Entrepreneurial Biotechnology(3 Spring)

BCHB-513 Core Concepts of Biochemistry & Molecular Biology(4 Fall)

BCHB-514, 515 Introduction to Bioinformatics(1 Fall/Spring)

BCHB-520 Financial Matrix for Biotechnology(1 Spring)

BCHB-523 Intellectual Property(1 Fall)

BCHB-526 Core Methods of Biotechnology(3 Fall)

BCHB-535 Programmed Cell Death(2 Fall)

BCHB-536 Applications of Cell Culture in Biotechnology & Medicine(2 Spring)

BCHB-543 Current Good Manufacturing Practices(1 Spring)

BCHB-910 Biochemistry/Molecular Biology Internship(4 Fall/Spring)

Graduate Electives, School of Arts & Sciences

BCHB-516 Molecular Medicine (2 Fall/Spring)

BCHB-521 Bioinformatics(3 Fall)

BCHB-522 Special Topics: Drug Target & Design(1 Spring)

BCHB-525 Immunobiotechnology(2 Spring)

BCHB-527 Food Biotechnology(2 Spring)

BCHB-529 Biotechnology-Based Human Diagnostics(2 Spring)

BCHB-533 Emerging Biotechnology Concepts(2 Spring)

BCHB-537 Principles and Practices of Fermentation(1 Spring)

BCHB-540 Molecular Basis of Carcinogenesis(3 Spring)

BCHB-541 Structural Biology(2 Spring)

BCHB-562 Applications of Biotechnology for World Agriculture(2 Fall)

BCHB-902 Biotechnology Tutorial(1-4, Fall/Spring)

BCHB-903 Biochemistry Tutorial(1-4, Fall/Spring)

PHAR-534 Ethical Issues in Scientific Research(2)

Business Electives

ACCT-101 Principles of Accounting(3)

ACCT-181 Business Law(3)

FINC-100 Fundamentals of Finance(3)

*School of Foreign Service Electives

STIA-402 Technology & Development(3)

STIA-420 Management and Technological Innovation(3)

STIA-444 Global Patterns of Disease(3)

STIA-446 International Politics of Health(3)

STIA-473 International Biotechnology(3)

* Courses under 500 must have instructor approval and tutorial form to receive graduate credit.

Course Descriptions

BCHB-502 Biotech Industry Internship (4 Fall, Spring, Summer), *CORE
For students in the business track, opportunities are available in industry, non-profits,
government agencies, technology transfer, and financial and law firms.  For the science
track, internships are available in various topics of the biomedical sciences at the
Georgetown University Medical Center or at NIH, FDA, NIST and the Walter Reed
Army Research Institute.
Professor: Chirikjian and Nontanovan

BCHB-507, 508 Laboratory Appl. of Biotechnology (3 Fall, 3 Spring) *CORE
A hands-on, laboratory-based course that introduces students to core techniques such as
electrophoretic analysis of nucleic acids and proteins, polymerase chain reaction (PCR),
Southern blotting, ELISA and western blotting, protein purification, and DNA
cloning.
Professor: Bazar, L., Helling, S., and Nontanovan, V.

BCHB-509 Introduction to the Biotechnology Industry (3 Fall), *CORE
Introduction to problems and opportunities of start-up biotechnology companies. The
course will take an in-depth look at various aspects of the Industry. Emphasis will focus
on established companies. Topics covered will include venture capital, intellectual
property, and career opportunities in biotechnology. Contributions will be made from
senior scientists and business managers from the biotechnology industry.
Instructor: Chirikjian, J.

BCHB-510 Entrepreneurial Biotechnology (3 Spring), *CORE
An in-depth look at various aspects of the biotechnology industry. Emphasis will
focus on start-up companies. Students will develop and report assigned case studies
on various biotechnology companies.
Professor: Chirikjian

BCHB-512 Global Biotechnology: Marketing and Business (1Spring)
Course will cover the Business and Marketing aspects of International Biotechnology
Instructors: Chirikjian, J., and Labuda, I

BCHB-513 Core Concepts of Biochemistry (4 Fall), *CORE
Survey of core concepts in biochemistry and molecular biology, with emphasis on
applications to biotechnology.
Professor: Rosenthal C. and Faculty

BCHB-514, 515 Introduction to Bioinformatics (1 Spring, Fall) *CORE
Introduction to bioinformatics with an emphasis on resources that are available and used in
biotechnology.
Professor: Vasudevan

BCHB-516 Molecular Medicine (2 Spring, Fall)
This course covers a variety of current biotechnology topics centered on the Biotech and
Pharmaceutical Industries approaches to the therapy of human diseases. Topics covered will
include: emerging trends in human diagnostics and the role of genetic/proteomic tools; systems
biology, synthetic biology, stem cell biology and personalized medicine in the future of medicinal
products.
Professor: Ascione

BCHB- 518 Introduction to Laboratory Applications in Biotechnology (3 Fall, Spring)
An introductory hands-on, laboratory-based course that introduces students to core techniques such as electrophoretic analysis of nucleic acids and proteins, polymerase chain reaction (PCR), Southern blotting, ELISA and western blotting, protein purification, tissue culture, DNA cloning, and Bioinformatics.
Instructor: Bazar, L

BCHB-520 Financial Matrix for Biotechnology (1 Spring)
Focuses on financial aspects of biotechnology companies. Emphasis will be placed on effective
management of companies.
Professor: Burleson, R., Gove, M., Morrow, M., and Hartwell, P.

BCHB-521 Bioinformatics (3 Spring)
Introduction to bioinformatics with an emphasis on resources that are available and uses in
biotechnology. The course includes lectures, computer labs, and projects. Students will
first be introduced to the An introductory level of computer science is recommended but
not required.
Professor: Danielsen and Mazumder

BCHB-522 Special Topics: Drug Target and Design (1 Spring)
The course objective is to furnish students with a comprehensive background in the history
of pharmacology and therapeutics leading to the current theory and practice of drug design
and the basic pharmacology, biochemistry, molecular biology and bioinformatic concepts
that drive it.
Professor: Eiden, L.

BCHB-523 Intellectual Property (1 Fall) *CORE
The course provides an opportunity to students to learn about intellectual property rights
and their uses in biotechnology. Topics addressed include: rights conferred by different
types of intellectual property; the uses of biotechnology patents; determining "patentability,"
interpreting the rights conferred by a patent; the patent-granting system in the US and elsewhere,
patent costs and values; and the post grant processes for enforcing and challenging US patents.
Technology licensing, royalty agreements and intellectual rights will be presented.
Professors: Millstein, L., and House, A.

BCHB-525 Immunobiotechnology (2 Spring)
An introduction to key concepts and applications of Immunology as is applied to the
biotechnology industry.
Professor: Kisailus, E. and Chirikjian, J.

BCHB-526 Core Methods of Biotechnology (3 Fall, Spring), *CORE
Introduction to core concepts of biotechnology.  Detailed description of methods used
for analysis, purification, quantitation of nucleic acids and proteins.  Topics include
applications of PCR, blotting techniques basics of cloning, basics of cell culture and
protein purification technology.
Instructors: Rosenthal D. and Bazar, L.

BCHB-527 - Food Biotechnology (2 Spring)
Applications of biotechnology as it relates to food production and taste enhancement.
Food Biotechnology course provides an introduction to the fascinating field of biotechnology
and its role in the food industry. With broad-brush strokes, it covers many facets of the
world of foods, which is very diverse yet very personal to all of us. The course touches
on topics related to food ingredients, fermentations, bioterrorism, FDA regulations, rapid
detection techniques of food born pathogens, chemical senses, nutrigenomics and
nutraceuticals.
Instructor: Labuda, I.

BCHB-529 - Biotechnology-Based Human Diagnostics (2 Spring),
Prerequisite: BCHB-513 or Equivalent
This lecture and laboratory course is designed to introduce biotechnology procedures as
they relate to medical applications for the development of human diagnostics.  Areas of
emphasis will include diagnostic tests for cancer, genetic diseases and the detection of
infectious agents.  There is a Laboratory component to this course, which emphasizes
PCR, immunology and immunohistology.
Instructors: Nontanovan, V. and Hartmann, D.

BCHB-533 Emerging Biotechnology Concepts (2 Spring)
An overview of selected new technologies that impact biotechnology and its applications.
The class will cover one or more emerging biotechnologies (advanced sequencing
techniques, their commercialization and their implications for society).  The impacts
and implications of sequencing technologies will be discussed.  Exiting markets,
technologies, limitations and economics will be examined.  The technologies underlying
new sequencing technologies will be explored.  The companies commercializing the
technologies will be presented.  Their economics and target markets will be reviewed,
and their IP portfolio will be examined and discussed.
Instructor: Millstein, L

BCHB-534 Environmental Biotechnology (1 Fall)
Environmental factors continue to be an area of continuous research because of their
potential as causes for human disease.  This course will concentrate on toxins and
chemicals that are exposed in our daily lives and their impact on DNA damage and
repair.  There is a laboratory component for this course.
Instructor: Ascione, R.

BCHB-535 Programmed Cell Death (2 Fall ) *CORE
The lecture and laboratory course familiarizes students with different pathways leading
to apoptosis and their importance in development as well as in diseases such as cancer and
neurodegeneration.
Professor: Rosenthal C.

BCHB-536 Appl. of Cell Culture in Biotechnology & Medicine (2 Spring ), *CORE
This lecture and laboratory course familiarizes students with different pathways leading
to apoptosis and their importance in development as well as in diseases such as cancer,
autoimmune diseases and neurodegenerative diseases such as Alzheimer's, Parkinson's,
and Ischemia.
Professor: Rosenthal, C.

BCHB-537 Principles and Practices of Fermentation (1 Fall/Spring)
Prerequisite: BCHB-507, 508 Lab Appl. of Biotechnology & Permission of the Instructor
Various aspects of fermentation will be introduced.  Students will have the opportunity to
grow cells to be used for extraction and purification of different biologics.
Instructors: Nontanovan, V. and Shiloach, J.

BCHB-538 Bioprocessing (1 Fall and Spring)
Prerequisite: BCHB-507, 508 Lab Appl. of Biotechnology
The course will emphasize purification and characterization of recombinant enzymes using
affinity and conventional chromatography.
Instructors: Bazar, L. and Nontanovan, V.

BCHB-540 Molecular Basis of Carcinogenesis (3 Spring)
In-depth discussions of the fundamental aspects of the mechanisms of carcinogenesis,
damage-responsive signal transduction, carcinogen-induced programmed cell death, genetic
diseases associated with defective repair, and anti-signaling drug design in the intervention
of the onset and progression of the carcinogenic process.
Instructors: Kasid, U. and Faculty

BCHB-541 Structural Biology (3 Spring)
The aim of the course is to provide the basic knowledge of the three-dimensional structures
of biomolecules (e.g., proteins, nucleic acids, etc) molecular structure determination techniques
as well as biological relevance of "structure-function" relationships.
Professor: Vasudevan, S.

BCHB-542 Basics of Structural Biology (2)
The aim of the course is to provide the basic concepts of three-dimensional structures
as determined by X-ray crystallography, NMR and electron microscopy. In addition
the course will cover fundamentals of structure-function relationships.
Instructor: Vasudevan, S.

BCHB-543 Current Good Manufacturing Practices (1 Spring)
This course is designed to familiarize students with Current Good Manufacturing Practices
(cGMP), the rules and regulations that guide the manufacture of FDA-approved
biopharmaceutical and biotechnology products.
Instructor: Mintz, C.

BCHB-544 Essentials of Biochemistry: Metabolism (2 Fall)
Survey of basic concepts in biochemistry, with emphasis on metabolism.
Instructor: Rosenthal, C.

BCHB-562 Applications of Biotechnology for World Agriculture (2 Fall)
This course will provide an overview of the issues--from the grandiose promises of
feeding the world and curing diseases to the doomsday rhetoric of poisoned children
and environmental collapse. It will focus on the implications of the new science and
on the interest groups that drive international battles over intellectual property rights,
the production and use of genetically modified plants and animals, and equity issues
between the biotechnology "have" and "have-not" nations.
Instructor: Lesney, M.

BCHB-590 Introduction to Internship (0 Fall, Spring and Summer)
Basic Preparation for the Internship
Instructors: Nontanovan, V. and Rosenthal, C

BCHB-602 Metabolic Biochemistry (2 Spring or P/F)
Prerequisite: BCHB-501 or BCHB-513 or Permission of the instructor.
Biochemical pathways focusing on energy metabolism including glycolysis,
citric acid cycle, oxidative phosphorylation, amino acid metabolism, urea
cycle, and fatty acid metabolism.
Instructors: Nakai, H. and Faculty

BCHB-902 Biotechnology Tutorial (1 to 4 Fall and Spring)
Tutorials with individual faculty.  Instructor Permission Required. 
Instructor: Chirikjian, J.

BCHB-903 Biochemistry Tutorial (1 to 4 Fall and Spring)
Tutorials with individual Faculty
Instructor Permission Required
Instructor: Rosenthal, C

BCHB-910 Biochemistry/Molecular Biology Internship (4 Spring, 4 Fall), *CORE
Students will pursue defined objectives in a research laboratory on campus or off-campus
(NIH, FDA, USDA, NMRC). Internships can be in various topics in the Biomedical Sciences,
including Biochemistry, Pharmacology, Cell Biology, Toxicology, Microbiology, Neurosciences,
and Oncology. Instuctor Permission Only
Professor: Rosenthal C

Updated: 7/20/10